PREN ISO 10927 : DRAFT 2009

Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
   3.1 Matrix assisted laser desorption/ionisation-time
       of flight-mass spectrometry (MALDI-TOF-MS)
   3.2 Molecular mass M
   3.3 Average molecular mass
4 Principle
5 Reagents
6 Apparatus
   6.1 General
   6.2 Sample introduction chamber/target
   6.3 Laser source
   6.4 Flight tube
   6.5 Detector
   6.6 Data recording
   6.7 Data handling
7 Procedure
   7.1 General
   7.2 Sample preparation
       7.2.1 Preparation of biopolymer/matrix solutions
   7.3 Instrument settings
   7.4 Spectra recording
8 Data acquisition and processing
   8.1 General
   8.2 Calibration
   8.3 Generation of mass calibration curve
   8.4 Intensity axis calibration
9 Expression of results
   9.1 Calculation of molecular mass distribution (MMD)
   9.2 Calculation of the molecular mass averages
10 Precision
11 Test report
Annex A (normative) - Calibrants
Bibliography

Defines a general method for determining the average molecular mass and molecular mass distribution of polymers [ref. 1] from 2000 g mol[-1] to 20000 g mol[-1] by matrix assisted laser desorption/ionization - time of flight - mass spectrometry (MALDI - TOF - MS).