BS EN 12128:1998

Foreword
Introduction
1 Scope
2 Normative references
3 Definitions
4 Physical containment level classification
5 Physical containment level 1 laboratory (PCL1)
6 Physical containment level 2 laboratory (PCL2)
7 Physical containment level 3 laboratory (PCL3)
8 Physical containment level 4 laboratory (PCL4)
Annex A (informative) Guidance on space needs and dimensions
Annex B (informative) Method of test for the determination
of pressure differences
Annex C (informative) Bibliography

Defines minimum physical requirements for biological safety for laboratories at four reference physical containment levels, appropriate for handling micro-organisms of differing risk groups. Mainly concerned with the containment of micro-organisms which could constitute a risk to human health. Applicable to microbiology laboratories where handling of micro-organisms in bacteriology, mycology, virology, parasitology and/or genetic modification is undertaken.

This European Standard specifies minimum physical requirements for biological safety for laboratories at four reference physical containment levels which are appropriate for handling micro-organisms of different risk groups.

This European Standard primarily addresses the containment of micro-organisms which can present a risk to human health.

It applies to microbiology laboratories where the handling of micro-organisms in bacteriology, mycology, virology, parasitology and/or genetic modification is carried out.

NOTE Some aspects can also be applicable to laboratories specializing in disciplines other than microbiology which deal with specimens or other material not intended for cultivation but which may contain micro-organisms.

The requirements given in this European Standard are to minimize risks that may result from handling micro-organisms or materials which contain them. They are applicable to premises where there is an intention to manipulate or propagate micro-organisms of known or unknown identity.