EN ISO 17099:2017

European foreword
Foreword
Introduction
1 Scope
2 Terms and definitions
3 Micronucleus assay methodology used in this standard
4 Confidentiality of personal information
5 Laboratory safety requirements
6 Calibration source(s), calibration curve, and minimum
   resolvable dose
7 Responsibility of the customer
8 Responsibility of the CBMN laboratory
9 Accidental overexposure involving few individuals
10 Population triage
11 Quality assurance and quality control
Annex A (informative) - Sample data sheet for recording micronuclei
        in binucleated cells
Annex B (informative) - Automation of micronuclei scoring
Annex C (informative) - Instructions for customer (sample)
Annex D (informative) - Sample questionnaire
Annex E (informative) - Sample of report for single assessment
Annex F (informative) - Example group sample report
Bibliography

ISO 17099:2014 addresses the following:a) confidentiality of personal information for the customer and the laboratory;b) laboratory safety requirements;c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;e) scoring criteria;f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;g) reporting of results;h) quality assurance and quality control;i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.