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BS ISO 19040-1:2018

BS ISO 19040-1:2018

Withdrawn

Withdrawn

A Withdrawn Standard is one, which is removed from sale, and its unique number can no longer be used. The Standard can be withdrawn and not replaced, or it can be withdrawn and replaced by a Standard with a different number.

Water quality. Determination of the estrogenic potential of water and waste water Yeast estrogen screen (Saccharomyces cerevisiae)

Amended by

BS EN ISO 19040-1:2022

Available format(s)

Hardcopy , PDF

Withdrawn date

11-10-2022

Language(s)

English

Published date

10-08-2018

Publisher

British Standards Institution

This document specifies a method for the determination of the estrogenic potential of water and
waste water by means of a reporter gene assay with genetically modified yeast strains Saccharomyces
cerevisiae. This

This document specifies a method for the determination of the estrogenic potential of water and waste water by means of a reporter gene assay with genetically modified yeast strains Saccharomyces cerevisiae. This reporter gene assay is based on the activation of the human estrogen receptor alpha.

This method is applicable to:

  • fresh water;

  • waste water;

  • aqueous extracts and leachates;

  • eluates of sediments (fresh water);

  • pore water;

  • aqueous solutions of single substances or of chemical mixtures;

  • drinking water.

The limit of quantification(LOQ) of this method for the direct analysis of water samples is between 8ng/l and 15ng/l 17β-estradiol equivalents(EEQ) based on the results of the international interlaboratory trial (see AnnexF). The upper threshold of the dynamic range for this test is between 120ng/l and 160ng/l 17β-estradiol equivalents(EEQ). Samples showing estrogenic potencies above this threshold have to be diluted for a valid quantification. Extraction and pre-concentration of water samples can prove necessary, if their estrogenic potential is below the given LOQ.

Committee
EH/3/5
DocumentType
Standard
ISBN
9780580847202
Pages
58
PublisherName
British Standards Institution
Status
Withdrawn

Standards Relationship
ISO 19040-1:2018 Identical

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Hardcopy - English
PDF - English
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